Structure-function relationships of the lrrc8 subunits and subdomains of the volume-regulated anion channel (vrac)

HIGHLIGHTS

• who: Devin K. Binder from the Max Planck Institute for Chemical Ecology, Germany Division of Biomedical Sciences, School of Medicine, University of California-Riverside, Riverside have published the research: Structure-function relationships of the LRRC8 subunits and subdomains of the volume-regulated anion channel (VRAC), in the Journal: (JOURNAL)
• how: The results indicated that single or double mutations to positions 2-4 as well as double mutations to positions 5 and 7 completely abolished VRAC Cl- currents (Zhou et_al 2018).
• future: Studies are needed to determine how different combinations of LRRC8B-E with . . .
  

   

  

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