HIGHLIGHTS
- who: Thomas Wiegand from the Université have published the research: The conformational changes coupling ATP hydrolysis and translocation in a bacterial DnaB helicase, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The study shows that most efficient DNA binding proceeds via the transition_state which prepares the conformation of the protein for DNA binding. In the first part of this study, the authors characterize the conformational events along the equivalence scheme for the ATP hydrolysis reaction (blue arrows in Fig 1b, for the nomenclature of the studied complexes see Fig 1c). The assumption that the seven . . .
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