Melatonin promotes sirtuin 1 expression and inhibits ire1 xbp1s chop to reduce endoplasmic reticulum mediated apoptosis in chondrocytes

HIGHLIGHTS

  • who: CHOP and colleagues from the Anhui Medical University have published the article: Melatonin promotes sirtuin 1 expression and inhibits IRE1 XBP1S CHOP to reduce endoplasmic reticulum mediated apoptosis in chondrocytes, in the Journal: (JOURNAL)
  • what: In this study the effects of melatonin on LPS-induced chondrocyte apoptosis were investigated, as were the potential mechanisms involved. The study was approved by the Research Ethics Committee of the First Affiliated Hospital of Anhui Medical University, china written informed consent was obtained from all individuals before their operations. For the first time, the experiment has confirmed the . . .

     

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