First-generation antipsychotic haloperidol alters the functionality of the late endosomal/lysosomal compartment in vitro

HIGHLIGHTS

  • who: Alberto Canfrán-Duque and collaborators from the Unidad Neurología Experimental, Hospital Universitario Ramón Cajal, IRyCIS, Madrid, Spain have published the research work: First-Generation Antipsychotic Haloperidol Alters the Functionality of the Late Endosomal/Lysosomal Compartment in Vitro, in the Journal: (JOURNAL)
  • what: The authors examined the effects of FGA haloperidol on the functionality of late endosomes/lysosomes in vitro. The authors show that haloperidol increases the alkalinity of lysosomes and affects the activity of enzymes located in this cellular compartment. The authors report for the first time that haloperidol can provoke . . .

     

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