Despr roles in tumor vasculo-angiogenesis, invasiveness, csc-survival and anoikis resistance: a ‘common receptor coordinator’ paradigm

HIGHLIGHTS

  • who: Invasiveness and colleagues from the Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America have published the research work: DEspR Roles in Tumor Vasculo-Angiogenesis, Invasiveness, CSC-Survival and Anoikis Resistance: A ‘Common Receptor Coordinator’ Paradigm, in the Journal: PLOS ONE | www.plosone.org of January/21,/2014
  • what: The authors show that functional analysis of the dual endothelin1/VEGFsignal peptide DEspR (formerly named Dear Chr.4q31.2) supports the putative common in pancreatic ductal adenocarcinoma (PDAC) and glioblastoma (GBM) selected for their CD133+CSCs . . .

     

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