Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting msh2

HIGHLIGHTS

• who: Ping Liu from the Using a simple random sampling, we collected , bone marrow specimens of AML patients from September , to May , at the Affiliated Hospital of Guizhou Medical UniversityDetails of clinical information are provided in Table, . Patient samples at diagnosis and relapse were collected, prior to treatment. Prior patient consent and approval from the Institutional Research Ethics Committee were obtained. Human AML cell lines Kasumi, and , were obtained from Guizhou Province Laboratory of Haematopoietic Stem Cell Transplantation Center. All human cell lines were tested for mycoplasma contamination and verified by short tandem repeat profiling. The cell . . .
  

   

  

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