The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile x syndrome

HIGHLIGHTS

  • who: Hongen Wei and collaborators from the Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China have published the research work: The Therapeutic effect of Memantine through the Stimulation of Synapse Formation and Dendritic Spine Maturation in Autism and Fragile X Syndrome, in the Journal: (JOURNAL) of May/15,/2012
  • what: The authors used cultured cerebellar granule cells (CGCs) from Fmr1 knockout (KO) mice a mouse model for fragile X syndrome (FXS) and syndromic autism to examine the effects of memantine on dendritic spine development and synapse formation. The authors demonstrate that memantine treatment . . .

     

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