Polyanionic carboxyethyl peptide nucleic acids (ce-pnas): synthesis and dna binding

HIGHLIGHTS

• who: Yuliya Kirillova and colleagues from the Department of Biotechnology and Bionanotechnology, Moscow State University of Fine Chemical Moscow State University, Moscow, Russia have published the research work: Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0140468]. October 15, 2015 of September/25,/2015
• what: The authors show that the modified γ-S-carboxyethyl-T10 PNA forms a stable triplex with polyadenine DNA. This study shows the first synthesis of three L-Glu-based polyanionic nucleic_acid mimics.
• how: The best results . . .
  

   

  

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