Erk8, a new member of the mitogen-activated protein kinase family*

HIGHLIGHTS

  • who: Mark K. Abe from the (UNIVERSITY) have published the research work: ERK8, a New Member of the Mitogen-activated Protein Kinase Family*, in the Journal: (JOURNAL) of December/31,/2001

SUMMARY

    The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Expression of ERK8 in COS cells and bacteria indicates that, in contrast to constitutively active ERK7, ERK8 has minimal basal kinase activity and a unique substrate profile. This result suggests that the TEY motif within the activation domain of wild-type ERK8 can be . . .

     

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