Palmitoylation of inducible nitric-oxide synthase at cys-3 is required for proper intracellular traffic and nitric oxide synthesis*

HIGHLIGHTS

  • who: Inmaculada Navarro-Le̕rida from the (UNIVERSITY) have published the Article: Palmitoylation of Inducible Nitric-oxide Synthase at Cys-3 Is Required for Proper Intracellular Traffic and Nitric Oxide Synthesis*, in the Journal: (JOURNAL) of June/14,/2004
  • what: Using radioactive fatty_acids, the authors show herein that NOS2 becomes thioacylated at Cys-3 with palmitic acid. The authors demonstrate in this article that the palmitoylation of NOS2 at Cys-3 is a process necessary for its intracellular transit toward subcellular domains where 䡠NO synthesis is required.
  • how: Immunofluorescence data indicated that all . . .

     

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