The coffee diterpene, kahweol, ameliorates pancreatic -cell function in streptozotocin (stz)-treated rat ins-1 cells through nf-kb and p-akt/bcl-2 pathways

HIGHLIGHTS

  • who: Waseem El-Huneidi and collaborators from the Department of Basic Medical Sciences, College of Medicine, University of Sharjah have published the article: The Coffee Diterpene, Kahweol, Ameliorates Pancreatic -Cell Function in Streptozotocin (STZ)-Treated Rat INS-1 Cells through NF-kB and p-AKT/Bcl-2 Pathways, in the Journal: Molecules 2021, 5167 of /2021/
  • what: This study showed that STZ treatment upregulated the expression of antioxidant proteins HMOX1 in addition to ID1 and 3. In sum, the study demonstrated that kahweol has a protective effect against STZ induced damage in pancreatic β-cells.
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