How hiv-1 integrase associates with human mitochondrial lysyl-trna synthetase

HIGHLIGHTS

  • who: Xaysongkhame Phongsavanh et al. from the Institute for Integrative Biology of the Cell (I BC), French Alternative Energies and Atomic Energy have published the research: How HIV-1 Integrase Associates with Human Mitochondrial Lysyl-tRNA Synthetase, in the Journal: Viruses 2020, 12, 1202 of /2020/
  • what: The authors show that integrases from HIV-1 and HIV-2 bind mLysRS with the same efficiency.
  • how: The authors conducted a detailed analysis of the complex of mLysRS with the integrase from HIV-1. The authors developed experimental and computational approaches to propose a structural . . .

     

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