Transformed canine and murine mesenchymal stem cells as a model for sarcoma with complex genomics

HIGHLIGHTS

  • who: Natasja Franceschini and colleagues from the Department of Pathology, Leiden University Medical Center, ZA Leiden, The Netherlands have published the article: Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics, in the Journal: (JOURNAL)
  • what: Canines too develop osteosarcoma, with a similar clinical and biological presentation as human osteosarcoma and the authors show here for the first time that canine MSCs can undergo spontaneous transformation.
  • how: In this study MSCs of and origin are used as a model to identify driver events for sarcomas with complex . . .

     

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