Nat10 acetylates bcl-xl mrna to promote the proliferation of multiple myeloma cells through pi3k-akt pathway

HIGHLIGHTS

  • who: Yuanjiao Zhang from the Guangzhou Medical University, China have published the Article: NAT10 acetylates BCL-XL mRNA to promote the proliferation of multiple myeloma cells through PI3K-AKT pathway, in the Journal: (JOURNAL)
  • how: WB results showed that Remodelin significantly promoted the expressions of cleaved-PARP and cleaved-Caspase 3 compared to non-treated cells . The data showed that the G0/G1 phase was decreased and the expressions of CDK4 and CDK6 were increased upon NAT10 overexpression in MM cells.

SUMMARY

    Multiple myeloma (MM) is a hematological cancer characterized by . . .

     

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