HIGHLIGHTS
- who: Aikaterini Tsiogka and collaborators from the (UNIVERSITY) have published the Article: The JAK/STAT Pathway and Its Selective Inhibition in the Treatment of Atopic Dermatitis: A Systematic Review, in the Journal: (JOURNAL) of 10/06/2022
SUMMARY
Atopic dermatitis (AD) is a chronic inflammatory skin disease with multifactorial pathophysiology, involving strong genetic predisposition, skin barrier dysfunction, microbiome abnormalities, immune dysregulation and extrinsic factors. Current knowledge suggests that robust activation of the T-helper (Th)-2 and Th22 (IL-22) immune_responses in both skin and serum play a pivotal role in the immunopathogenesis . . .
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