Covid-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy

HIGHLIGHTS

• who: Giuseppe Novelli from the (UNIVERSITY) have published the research work: COVID-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy, in the Journal: (JOURNAL) of March/31,/2021

SUMMARY

The D614G mutation determines an important conformational change in the spike_protein between the S1 and S2 domains, that favors the binding to the angiotensinconverting enzyme 2 (ACE2) receptor and thus increases the probability of infection: presumably the key to this variant having become globally dominant. Variants from this particular lineage are associated with multiple amino_acid changes in . . .

 



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