A new constitutively active brain pak3 isoform displays modified specificities toward rac and cdc42 gtpases*

HIGHLIGHTS

• who: VeÌ?ronique Rousseau from the (UNIVERSITY) have published the research: A New Constitutively Active Brain PAK3 Isoform Displays Modified Specificities toward Rac and Cdc42 GTPases*, in the Journal: (JOURNAL) of July/19,/2002
• what: The authors report the first characterization of a splice variant of the mouse PAK3 gene the authors isolated from brain mRNA.
• how: Kinase Activity-Since the alternatively spliced exon b is located within the N-terminal regulatory domain of PAK3 the authors investigated whether its expression might interfere with the intrinsic kinase activity in an in_vitro kinase assay . . .
  

   

  

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