Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo *

HIGHLIGHTS

• who: Xiaohua Xin from the (UNIVERSITY) have published the Article: Peroxisome Proliferator-activated Receptor γ Ligands Are Potent Inhibitors of Angiogenesis in Vitro and in Vivo *, in the Journal: (JOURNAL) of November/25,/1998
• what: The authors report that human umbilical vein endothelial cells (HUVEC) express PPARg mRNA and protein. The authors report on the potent and novel inhibitory activity of PPARg ligands on HUVEC differentiation into tubelike structures and proliferation in_vitro, and the inhibition of VEGF elicited angiogenesis in_vivo. The expression of PPARa mRNA in HUVEC has been previously reported ; however, this study shows for . . .
  

   

  

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