Hendra virus fusion protein transmembrane domain contributes to pre-fusion protein stability

HIGHLIGHTS

• who: Stacy Webb from the Stacy Webb, Tamas Nagy, Hunter Moseley, Michael Fried, and Rebecca Dutch, From the Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky , Edited by Charles ESamuel Enveloped viruses utilize fusion (F) proteins studding the surface of the virus to facilitate membrane fusion with a target cell membrane. Fusion of the viral envelope with a cellular membrane is required for release of viral genomic material, so the virus can ultimately reproduce and spread. To drive fusion, the F protein undergoes an irreversible conformational change, transitioning from a metastable pre-fusion conformation . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.