HIGHLIGHTS
- who: Donna J. Lowe from the Centre University of have published the research work: Chronic irradiation of human cells reduces histone levels and deregulates gene expression, in the Journal: Scientific Reports Scientific Reports of 11/09/2019
- what: The authors report that radiation exposures estimated to inflict fewer than one DSB per hour per cell, decreased cell proliferation and increased cellular senescence. The authors show that these changes are associated with pronounced changes in gene_expression, causing alterations in protein expression, some of which are pro-inflammatory and reflect an aged-cell phenotype. The authors discuss . . .
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