HIGHLIGHTS
- who: Shirley Gil-Parrado from the (UNIVERSITY) have published the research work: Ionomycin-activated Calpain Triggers Apoptosis, in the Journal: (JOURNAL) of March/27,/2002
- what: The authors report that the calcium ionophore ionomycin promotes apoptosis in LCLC 103H cells, a cell line derived from a human large cell lung carcinoma . Next, the authors aimed to identify calpain substrates associated with the observed cell death processes. Consistent with these results, the authors report here that calpain activation triggered by transient calcium concentration increases to 0.8 -1.5 M, induced by addition of 2 M . . .
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