Differential regulation of cdc2 and cdk2 by ringo and cyclins*210

HIGHLIGHTS

  • who: Anthi Karaiskou from the (UNIVERSITY) have published the research work: Differential Regulation of Cdc2 and Cdk2 by RINGO and Cyclins*210, in the Journal: (JOURNAL) of May/23,/2001
  • what: The authors report that, in contrast with Cdc2cyclin complexes, the phosphorylation of Thr-161 is not required for full activation of Cdc2 by RINGO.
  • how: To distinguish between these two possibilities the authors compared the effect of wild_type Cak1/Civ1 and a kinase-inactive Cak1/Civ1 mutant on the RINGO-induced H1 kinase activity of the F60 fraction (Fig 1F). Myt1 Inhibits . . .

     

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