Inactivating mutations of the ik gene weaken ku80/ku70-mediated dna repair and sensitize endometrial cancer to chemotherapy

HIGHLIGHTS

  • who: Chao Gao and collaborators from the Department of Cancer Biology, Wake Forest Baptist Comprehensive Cancer Center, Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin, China have published the article: Inactivating Mutations of the IK Gene Weaken Ku80/Ku70-Mediated DNA Repair and Sensitize Endometrial Cancer to Chemotherapy, in the Journal: (JOURNAL)
  • what: This study provides insight into how IK somatic mutations contribute to EC pathophysiology. The experiments demonstrated that IK attenuation sensitized EC cells to cisplatin treatment in_vitro and in_vivo. The authors . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?