A potential role for huwe1 in modulatingcisplatin sensitivity

HIGHLIGHTS

  • who: Stijn Wenmaekers et al. from the Laboratory Translational Oncology, University Medical Center Utrecht, CX Utrecht, The Netherlands have published the article: A Potential Role for HUWE1 in ModulatingCisplatin Sensitivity, in the Journal: Cells 2021, 10, 1262. of 18/05/2021
  • what: By addressing this topic, the authors aim to provide a mechanistic framework in support of the recent observations on HUWE1 in bladder cancer . Thereby, this review provides a mechanistic framework in which HUWE1 deficiency is proposed as a potent multifactorial driver of resistance to platins.
  • future: Another future direction could be . . .

     

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