Identification of a common pharmacophore for binding to mmp2 and rgd integrin: towards a multitarget approach to inhibit cancer angiogenesis and metastasis

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  • who: Lorenzo Baldini et al. from the Department of Chemistry "Ugo Schiff", University of Florence, Sesto Fiorentino, Italy have published the Article: Identification of a Common Pharmacophore for Binding to MMP2 and RGD Integrin: Towards a Multitarget Approach to Inhibit Cancer Angiogenesis and Metastasis, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW 18 of /2022/
  • what: All the experiments were performed in triplicates and data collected were analyzed using Graphpad 5.0 Software Package (GraphPad Prism Inc .
  • how: Considering the poor efficacy of monotherapies the authors reasoned combining the inhibition of . . .

     

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