HIGHLIGHTS
- who: Daniel Finke and colleagues from the Department of Cardiology, Heidelberg University Hospital, Heidelberg, Germany have published the paper: Comparative Transcriptomics of Immune Checkpoint Inhibitor Myocarditis Identifies Guanylate Binding Protein 5 and 6 Dysregulation, in the Journal: (JOURNAL)
- what: The authors aimed to characterize the transcriptional changes of myocardial biopsies and their possible implications. The authors propose an involvement of the inflammasome in the pathophysiology of ICIM, which plays a minor role in other cardiac pathologies, such as DCM or VIM. The study reports transcriptional profiling of ICIM and reveals the involvement of CD8 and . . .
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