Molecular determinants of ca 1.2 calcium channel inactivation

HIGHLIGHTS

  • who: Nikolai M. Soldatov from the Humgenex Inc, Kensington, MD, USA have published the research work: Molecular Determinants of Ca 1.2 Calcium Channel Inactivation, in the Journal: (JOURNAL) of 24/08/2012
  • what: This paper has demonstrated that we know how to accelerate inactivation of Cav 1.2 to τ f less than 10 ms (Figure 3(C)), to deprive it from inactivation completely (Figures 4(B) and 4(C)), or to eliminate dependence of its expression from β or α2 δ without significant consequences for inactivation.

SUMMARY

    The auxiliary β and α2 δ subunits . . .

     

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