Metabolic changes in glucose transporter-deficient leishmania mexicana and parasite virulence*

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• who: Dayana Rodri̕guez-Contreras from the Dayana Rodrı́guez-Contreras and Scott MLandfear, From the Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon , Leishmania mexicana are parasitic protozoa that express a variety of glycoconjugates that play important roles in their biology as well as the storage carbohydrate ␤-mannan, which is an essential virulence factor for survival of intracellular amastigote forms in the mammalian host. Glucose transporter null mutants, which are viable as insect form promastigotes but not as amastigotes, do not take up glucose and other hexoses but are still able . . .
  

   

  

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