Myelin pathology: involvement of molecular chaperones and the promise of chaperonotherapy

HIGHLIGHTS

  • who: Federica Scalia and colleagues from the Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Baltimore-Institute of Marine and Environmental Technology (IMET), Baltimore, MD, USA have published the article: Myelin Pathology: Involvement of Molecular Chaperones and the Promise of Chaperonotherapy, in the Journal: (JOURNAL)
  • how: The results indicated that non-myelinating and myelinating glial cells respond to 7 of 11 EC137 (a small_molecule inhibitor of Hsp90) by increased expression of chaperones including Hsp70 Hsp27 and αB-crystallin.
  • future: Note the list of myelin disorders primarily or secondarily dependent on . . .

     

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