Chronic modafinil therapy ameliorates depressive-like behavior, spatial memory and hippocampal plasticity impairments, and sleep-wake changes in a surgical mouse model of menopause

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• who: Yu-Dong Yan from the Female C BL/, mice were at eight to ten weeks of age at the start of each experimentThey were housed four to five per cage with access to food and water ad libitum at a constant temperature (22, °C) and humidity (40-60%), with a, h light (inactive)/dark (active) cycle (lights on at, :00). The animals were randomly allocated in each experiment. All experimental protocols performed were approved by the Committee on the Ethics of Animal Experiments in the School of Basic Medical Sciences at Fudan University, with license identification . . .
  

   

  

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