HIGHLIGHTS
- who: Mingyang Ma from the (UNIVERSITY) have published the article: p53 positively regulates the proliferation of hepatic progenitor cells promoted by laminin-521, in the Journal: (JOURNAL) of 16/03/2022
- what: Although the mechanisms responsible for the upregulation of p53 protein levels in proliferating HPCs are still unclear, the authors provide evidence for the involvement of Akt-dependent and ERK-independent signaling in the LN-521 induced accumulation of p53 in proliferating HPCs. In this study, the transcriptional changes of laminin constituents were examined and a rapid burst in the transcription levels of Lama2 . . .
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