Structure of a nucleosome-bound muvb transcription factor complex reveals dna remodelling

HIGHLIGHTS

  • who: Marios G. Koliopoulos from the (UNIVERSITY) have published the Article: Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling, in the Journal: (JOURNAL) of 23/02/2022
  • what: Given the remodelling activity on the nucleosome, the authors propose that the MuvB:B-MYB complex functions as a pioneer transcription factor complex. The authors rationalise prior biochemical and cellular studies and provide a molecular framework of interactions on a protein complex that is key for cell cycle regulation. This analysis shows 2 a MMB Proline-rich loop LIN37 LIN9 DIRP TUDOR Coiled . . .

     

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