Causes and pathophysiology of acquired sideroblastic anemia

HIGHLIGHTS

  • who: Juan Jose Rodriguez-Sevilla and colleagues from the Department of Hematology, Hospital del Mar, Barcelona, Spain have published the article: Causes and Pathophysiology of Acquired Sideroblastic Anemia, in the Journal: Genes 2022, 1562 of /2022/
  • future: The mechanism of vacuole and ring sideroblasts formation may be mitochondrial injury however further studies are needed to clarify its specific mechanism.

SUMMARY

    Genes13091562 Ring sideroblasts are erythroblasts with an abnormal accumulation of iron in their perinuclear mitochondria, and their presence defines sideroblastic anemias. In 1945, Cooley described a patient with sex-linked anemia . . .

     

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