Broad-spectrum small-molecule inhibitors of the sars-cov-2 spike—ace2 protein-protein interaction from a chemical space of privileged protein binders

HIGHLIGHTS

• who: Sung-Ting Chuang and Peter Buchwald from the Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL, USA have published the Article: Broad-Spectrum Small-Molecule Inhibitors of the SARS-CoV-2 Spike—ACE2 Protein-Protein Interaction from a Chemical Space of Privileged Protein Binders, in the Journal: Pharmaceuticals 2022, 1084 of 19/08/2022
• what: The authors show that in addition to the original SARS-CoV-2 strain these SMIs also inhibit this PPI for variants of concern including delta (B.1.617.2) and omicron (B.1.1.529 . . .
  

   

  

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