Inhibition of autophagy potentiates the cytotoxicity of the irreversible fgfr1-4 inhibitor fiin-2 on lung adenocarcinoma

HIGHLIGHTS

  • who: Xiuqin Jia from the (UNIVERSITY) have published the paper: Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma, in the Journal: (JOURNAL) of 12/02/2022
  • what: The authors selected the representative human LUAD cell lines of A549 and cisplatin-resistant A549/DDP to investigate the antitumor effects of FIIN-2 and clarify the relationship between FIIN-2 and autophagy in LUAD.
  • how: The mRNA expression levels were normalized using β-actin and the results were calculated by the 2-ΔΔCt method. The results showed . . .

     

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