HIGHLIGHTS
- who: Physicochemical-guided design et al. from the CentroUniversidade have published the research work: Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential, in the Journal: Scientific Reports Scientific Reports
- how: This paper describes two new synthetic peptides (BotrAMP14 and CrotAMP14) derived from the vipericidins batroxicidin and crotalicidin18 which were generated by a physicochemical-guided design strategy aiming to reduce their size as well as preserve or improve the antibacterial properties and low toxicity of their parent peptides.
SUMMARY
AMPs can range in length from 2 . . .
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