Viscum album-mediated cox-2 inhibition implicates destabilization of cox-2 mrna

HIGHLIGHTS

  • who: Chaitrali Saha and collaborators from the 138, France have published the research work: Viscum album-Mediated COX-2 Inhibition Implicates Destabilization of COX-2 mRNA, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0114965]. February 9, 2015 of July/25,/2014
  • what: Using cyclohexamide pulse chase experiment the authors demonstrate that COX2 protein degradation is not affected by the treatment with VA whereas experiments on transcriptional blockade with actinomycin D revealed a marked reduction in the half life of COX-2 mRNA due to its rapid degradation in the cells treated with . . .

     

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