HIGHLIGHTS
- who: Frank A. E. Kruyt from the Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands COSS, France have published the paper: Multiple Interactions Between Cancer Cells and the Tumor Microenvironment Modulate TRAIL Signaling: Implications for TRAIL Receptor Targeted Therapy, in the Journal: (JOURNAL)
- what: In this review, the authors focus on the impact of the TME on the outcome of TRAIL signaling in tumor cells.
- how: Intriguingly in this study no differences were detected on primary tumor formation however Trail-R deficient mice showed enhanced metastatic spread to . . .
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