HIGHLIGHTS
- who: Lambertus P. W. J. van den Heuvel from the Leibniz Institute for Natural Product Biology, Germany Uppsala University, Sweden have published the research: Novel Assays to Distinguish Between Properdin-Dependent and Properdin-Independent C3 Nephritic Factors Provide Insight Into Properdin-Inhibiting Therapy, in the Journal: (JOURNAL)
- what: The authors established methods to distinguish between properdin-dependent and properdin-independent C3NeFs and subsequently investigated whether convertase stabilization could be normalized by properdin inhibition in patients with properdin-dependent C3NeFs. As an alternative approach, the authors aimed to assess the properdin dependency of C3NeFs directly in . . .
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