Connexin40 controls endothelial activation by dampening nf κ b activation

HIGHLIGHTS

  • who: Top from the Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland have published the article: Connexin40 controls endothelial activation by dampening NF κ B activation, in the Journal: (JOURNAL)
  • what: The authors investigated the relation between shear stress Cx40 and NFκB. The study demonstrates that Cx40 and IκBα are interacting proteins.

SUMMARY

    Three connexins are expressed in arterial ECs, i.e. Cx37, Cx40 and Cx43. Effect of shear stress on in_vivo and in_vitro Cx40 expression To investigate possible effects of shear stress on endothelial Cx40 expression, the . . .

     

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