HIGHLIGHTS
- who: A Topol from the (UNIVERSITY) have published the research: Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients, in the Journal: (JOURNAL)
- what: The authors report increased total protein levels and global protein synthesis in SZ hiPSC NPCs, but not SZ hiPSCs or hiPSC neurons, derived from four SZ patients.
- future: To resolve these inconsistencies future studies must compare many more hiPSC-derived neural cell types (glutamatergic GABAergic and dopaminergic neurons as well as astrocytes) across larger cohorts and should ideally include patient-matched ONS . . .
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