The calcium channel proteins orai3 and stim1 mediate tgf-β induced snai1 expression

HIGHLIGHTS

  • who: Top from the Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA have published the Article: The calcium channel proteins ORAI3 and STIM1 mediate TGF-β induced Snai1 expression, in the Journal: (JOURNAL)
  • what: The authors show that blocking store-operated calcium entry (SOCE) with 2-aminoethoxydiphenylborane (2APB) reduces cell migration but paradoxically increases the level of dependent Snai1 gene activation. Next, the authors show here that the 2APB dependent amplification of the TGF-β induced Snai1 gene activation occurs in part via the AKT and NF . . .

     

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