A fluorescence-based high-throughput assay for the discovery of exchange protein directly activated by cyclic amp (epac) antagonists

HIGHLIGHTS

  • who: Cyclic AMP (EPAC) Antagonists and colleagues from the Department of Pharmacology and Toxicology and Sealy Center for Structural Biology and Molecular Biophysics, The University of Texas Medical Branch, Galveston, TexasEditor: Rafael Linden, Universidade Federal do Rio de Janeiro, Brazil have published the article: A Fluorescence-Based High-Throughput Assay for the Discovery of Exchange Protein Directly Activated by Cyclic AMP (EPAC) Antagonists, in the Journal: (JOURNAL) of January/19,/2012

SUMMARY

    CAMP-mediated signaling regulates a myriad of important biological processes under both physiological and pathological conditions. In multi-cellular eukaryotic organisms . . .

     

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