HIGHLIGHTS
- who: Nagendra Kumar Kaushik and colleagues from the Plasma Bioscience Research Center, Kwangwoon University, Seoul, KoreaDepartment of Chemistry, University of Delhi, Delhi, India have published the research: Biomedical Importance of Indoles, in the Journal: Molecules 2013, 18, 6620-6662 of 17/04/2013
- what: Indole derivatives are very important heterocyclic compounds in the drug-discovery studies.
- how: Their results showed that steric parameters (MR) are highly correlated with biological activity. Their pharmacological data indicated that introduction of indole core improved the anti-tumor activity of the 46-diaryl-2-amino-3-cyanopyridines.
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