Tuning of liver sieve: the interplay between actin and myosin regulatory light chain regulates fenestration size and number in murine liver sinusoidal endothelial cells

HIGHLIGHTS

• who: Bartlomiej Zapotoczny and colleagues from the Vascular Biology Research Group, Department of Medical Biology, University of Troms31, Kraków, Poland have published the research: Tuning of Liver Sieve: The Interplay between Actin and Myosin Regulatory Light Chain Regulates Fenestration Size and Number in Murine Liver Sinusoidal Endothelial Cells, in the Journal: (JOURNAL)
• what: The authors show that in LSEC, both phosphorylation and dephosphorylation of MLC results in an altered fenestration number and diameter. Preliminary data obtained in this study showed no effect below 20 µM. The authors show that CytB, by affecting actin, would . . .
  

   

  

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