Intermittent caloric restriction promotes erythroid development and ameliorates phenylhydrazine-induced anemia in mice

HIGHLIGHTS

  • who: Yan Chen from the Yangzhou University, China have published the article: Intermittent Caloric Restriction Promotes Erythroid Development and Ameliorates Phenylhydrazine-Induced Anemia in Mice, in the Journal: (JOURNAL)
  • what: The authors demonstrated that a short-term intermittent CR, but not continuous CR, has a significant effect to promote extramedullary hematopoiesis in the spleen and such activity can ameliorate PHZ-induced acute anemia in the mouse.
  • how: Collectively these data indicated that intermittent CR but not continuous CR can promote differentiation of HSC/MPP into committed erythroid progenitors consistent with the finding that . . .

     

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