HIGHLIGHTS
- who: Amber Lockridge from the Duve Institute, Lille University of Science and Technology, France have published the paper: A nexus of lipid and O-Glcnac metabolism in physiology and disease, in the Journal: (JOURNAL)
- what: Loss of OGT in the brain and peripheral tissues lead to specific changes in HFD hyperphagia, implicating OGlcNAcylation in hedonic eating. aCaMKII-CreERT2 Ogt KO mice were hyperphagic under standard chow conditions but HFD feeding failed to further potentiate this in either of the studies described previously. Basal lipolysis is not significantly altered in the models described above but was . . .
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