Targeting syk in autoimmune rheumatic diseases

HIGHLIGHTS

  • who: Guo-Min Deng from the Saint Louis University, USA have published the research: Targeting Syk in Autoimmune Rheumatic Diseases, in the Journal: (JOURNAL)
  • what: Inhibitors of Syk devoid of side effects should prove of great clinical value.

SUMMARY

    Spleen tyrosine kinase (Syk) is a cytoplasmic protein-tyrosine kinase and a member of the Src family of non-receptor tyrosine kinases. In this review, the authors discuss the role of Syk in Fcγ receptor (FcγR) signaling and the effect of Syk inhibitor in treatment of autoimmune diseases. The Role of . . .

     

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