Physicochemical and biological analysis of synthetic bacterial lipopeptides

HIGHLIGHTS

• who: Andra B. Schromm from the (UNIVERSITY) have published the Article: Physicochemical and Biological Analysis of Synthetic Bacterial Lipopeptides, in the Journal: (JOURNAL) of April/13,/2007
• what: Using human macrophages differentiated from peripheral blood mononuclear cells, the authors show here that lipolan is also able to antagonize cell activation by LPS in human macrophages, as shown by the reduction in TNF␣ production in the presence of lipolan.
• how: When the authors investigated the TLR dependence of the inhibition of cell activation by LPS it turned out that the antagonistic activity was independent . . .
  

   

  

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