Targeted perikaryal-specific brain lesions with excitotoxins

HIGHLIGHTS

  • who: α-amino- and colleagues from the McLean Hospital, Harvard Medical School, Belmont, MA, United States, Maryland Psychiatric Research Center, University have published the article: Targeted Perikaryal-Specific Brain Lesions With Excitotoxins, in the Journal: (JOURNAL)
  • what: Frontiers in Neuroscience | www.frontiersin.org Olney (1969a), this study demonstrated neuronal degeneration in the hypothalamus resulting from neonatal treatment of mice with monosodium glutamate that resulted in a striking phenotype including stunted growth, blindness and obesity. Olney et_al , this study demonstrated a close correlation between excitatory potency and neurotoxicity of systemically administered analogs of L-glutamate, prompting the . . .

     

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